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Ann Intern Med

AI gets Choosing Wisely right, but stumbles on a few low-value tests

Large language models rarely withheld appropriate care, though some frequently recommended thyroid ultrasound and ECGs that guidelines advise against. . .

JAMA Netw Open

Home brain stimulation plus gaming: Feasible, but effective?

Patients completed treatment reliably, but the depression intervention offered no benefit over a double-sham control. . .

Company news

FDA OKs Enspryng, first at-home injection for thyroid eye disease

Monthly maintenance dosing offers patients an alternative to infusion visits…

JAMA Neurol

Anti-CGRP migraine biologics linked to higher miscarriage risk

Early pregnancy exposure to anti-CGRP antibodies was associated with a 42% higher risk of spontaneous abortion, while propranolol showed no increased risk. . .

Company news

FDA approves Ryzumvi for presbyopia

New indication expands treatment choices for adults with age-related near vision loss. . .

Obstet Gynecol

10h

New ACOG guidance expands menopause treatment options

Updated recommendations endorse newer nonhormonal therapies while reaffirming hormone therapy for eligible patients. . .

JAMA Netw Open

13h

ADHD linked to higher risk of death from multiple causes

Meta-analysis of 19 studies found increased risks of suicide, injury-related, and natural-cause death among people with ADHD, while medication use was associated with lower overall mortality. . .

Biol Psychiatry Cogn Neurosci

Children’s caffeine intake may offer clues about sleep and mental health

Soft drinks drove most associations, highlighting an easily overlooked part of pediatric sleep and behavioral assessments. . .

Ann Intern Med

What’s at stake when the Hep B birth dose is skipped?

Model projects 83% more chronic childhood infections under shared decision making. . .